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Advancing Regenerative Medicine
with Group Synergy
~ Building on Sumitomo Pharma’s expertise, powered by
the Sumitomo Chemical Group ~
RACTHERA builds on Sumitomo Pharma’s long-standing research in neural regeneration, which began
in the 1990s. In the 2010s, this work evolved into active research and development of regenerative medicine
using iPS cells. These efforts now serve as the foundation of our regenerative and cell therapy business. This
rich history forms the foundation of our current regenerative and cell therapy business. Over the years, we have
steadily developed a comprehensive process that spans research, manufacturing, and commercialization.
Our business is guided by three core principles:
Open Innovation
Networks
- Collaboration within the Sumitomo Chemical Group
- Partnerships with academia and ventures
- Cross-industry alliances
Front Runner in Practical
Application of iPS Cells
- Differentiation technologies from pluripotent stem cells
- Proven track record in addressing urgent needs in Japan and the U.S.
- Possession of iPS cell lines ready for commercial use
Manufacturing Capability
- Close collaboration with S-RACMO
- Expertise in cell manufacturing and process development
- Manufacturing infrastructure and skilled personnel
From the Central Nervous System and
Eye to Broader Therapeutic Areas
We began our journey in areas such as the central nervous system and the eye, where fewer cells are required and immune responses are less likely—making them ideal for cell transplantation. As our iPS cell differentiation technologies have advanced, we are now expanding into more complex areas, including peripheral organs, where medical needs are high and therapeutic possibilities are growing.
Open Innovation
Networks
- Collaboration within
the Sumitomo Chemical Group - Partnerships with
academia and ventures - Cross-industry alliances
From CNS/Eye to Broader
Therapeutic Areas
From Japan to Global
Japan is the birthplace of iPS cell technology and offers a rich ecosystem for stem cell
research and clinical application. With a dedicated regulatory pathway for regenerative medicine, Japan
enables early practical use of these therapies.
Our strategy is to first achieve success in Japan, then expand globally—especially to markets like the United
States—so we can bring regenerative medicine to more patients and grow our business internationally.
Front Runner in Practical
Application of iPS Cells
- Differentiation technologies from pluripotent stem cells
- Proven track record in addressing urgent needs in Japan and the U.S.
- Possession of iPS cell lines ready for commercial use
From Japan to Global
From Single Cells to Complex
Tissues and Organs
Cell therapies range from single-cell products to complex 3D tissues and organs. Single-cell
therapies are easier to produce and manage, and are effective for diseases affecting specific cell types.
For more complex conditions, we are developing advanced tissue structures using technologies like organoids.
These therapies require overcoming technical challenges but offer broader applications and greater impact.
We currently focus on allogeneic transplantation, using iPS cells derived from healthy donors to create
high-quality cell therapy products. Looking ahead, we are exploring:
Autologous transplantation, using a patient’s own iPS cells for personalized treatment
Next-generation cell therapies, enhanced through genome editing technologies.
Manufacturing Capability
- Close collaboration with S-RACMO
- Expertise in cell manufacturing and process development
- Manufacturing infrastructure and skilled personnel
From Single Cells to Complex
Tissues and Organs
Through these efforts, RACTHERA is committed to delivering safe, effective, and transformative regenerative therapies to patients around the world.